Combination of analgesics (NSAIDS), baclofen, clonidine and a single dose of buprenorphine for heroin detoxification
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چکیده
Background: Heroin dependency is currently an alarming problem. Objective: To investigate the efficacy of combination of analgesics (NSAIDS), baclofen, clonidine and a single high dose of buprenorphine in heroin detoxification. Results: Administration of combination of, baclofen 75 mg, clonidine 0.2 mg, ibuprofen 1200 mg and a single 57 mg of buprenorphine is very effective for detoxification of heroin dependence. Discussion: This study clarifies that a combination of analgesics (NSAIDS), baclofen, clonidine and a single high dose of buprenorphine is quite helpful in the management of heroin withdrawal symptoms. Hence, our study may be a substantial addition to the literature. Conclusions: We resulted that a combination of analgesics (NSAIDS), baclofen, clonidine and a single high dose of buprenorphine is very helpful in the detoxification of heroin withdrawal symptoms.
منابع مشابه
A Comparison of the Efficacy of Buprenorphine and Clonidine in Detoxification of Heroin-Dependents and the Following Maintenance Treatment
Abstract Background: This study compared the success rates of buprenorphine and clonidine in detoxification of heroin-dependents and evaluated the recurrence of drug abuse in patients taking naltrexone in a 6 month follow up. Methods: A double-blind study was carried out in Kerman’s psychiatric hospital on heroin-dependents seeking detoxification during the years 2007-2009.These patient...
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Previous studies comparing buprenorphine and clonidine provided little information about subjective factors associated with the effective management of opioid withdrawal. This study sought to compare detoxification programs using these medications with regard to side-effects and related distress, general well-being, perceived self-efficacy and social support. A total of 200 treatment-seeking he...
متن کاملAnesthesia-assisted vs buprenorphine- or clonidine-assisted heroin detoxification and naltrexone induction: a randomized trial.
CONTEXT Rapid opioid detoxification with opioid antagonist induction using general anesthesia has emerged as an expensive, potentially dangerous, unproven approach to treat opioid dependence. OBJECTIVE To determine how anesthesia-assisted detoxification with rapid antagonist induction for heroin dependence compared with 2 alternative detoxification and antagonist induction methods. DESIGN, ...
متن کاملA Comparison of the Efficacy of Buprenorphine and Clonidine in Detoxification of Heroin-Dependents and the Following Maintenance Treatment
BACKGROUND This study compared the success rates of buprenorphine and clonidine in detoxification of heroin-dependents and evaluated the recurrence of drug abuse in patients taking naltrexone in a 6 month follow up. METHODS A double-blind study was carried out in Kerman's psychiatric hospital on heroin-dependents seeking detoxification during the years 2007-2009.These patients were randomized...
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تاریخ انتشار 2016